Examining estradiols neuroprotective abilities and mechanisms of action in cerebrovascular accidents and neurodegenerative conditions
DOI :
https://doi.org/10.18192/osurj.v1i1.3699Résumé
Les estrogènes sont connus pour les rôles essentiels qu’ils jouent dans le corps. Ces hormones exercent des actions protectrices cruciales face aux dommages neuronaux. De nombreuses études ont fourni une profonde compréhension de ces actions uniques qui vont bien au-delà de la portée de la reproduction et la régulation de la reproduction. En tenant compte des divers mécanismes, itinéraires de livraison, niveaux de dosage, l’âge et l’état de santé des personnes recevant un traitement, l’hormone peut être utilisée comme protection contre la mort neuronale. Cet article examine les découvertes qui composent l’ensemble de connaissances actuelles en ce qui concerne les estrogènes en tant que neuro-protecteurs contre les accidents vasculaires cérébraux (AVC) et les maladies neurodégénératives. Ces résultats ont de grandes implications pour l’amélioration de la qualité de la vie pour la population vieillissante. Ils donnent un aperçu de l’impact des hormones sur la protection des tissus neuronaux et initient une discussion entre les membres de la communauté scientifique, veillant à ce que les futures études cliniques utilisent des méthodes qui maximisent la qualité des résultats obtenus.
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