Celiac Disease and Maternal Infertility and Pregnancy Outcomes: Is Screening Necessary?

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Published: Dec 18, 2017
DOI: https://doi.org/10.18192/uojm.v7i2.2194
Keywords:
Celiac Disease, Infertility, Fetal Outcome, Screening

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Syed Mohammad
University of Ottawa
Kai Wu
University of Ottawa
Johnny Huang
University of Ottawa

Abstract

Celiac disease is a common autoimmune condition that is often underappreciated in pregnant women. Due to the difficulty in conducting high-quality studies involving pregnant patients, the evidence supporting the association between celiac disease and maternal fertility and pregnancy outcome, and the benefits of screening for celiac disease in this population are unclear. Therefore, we sought to review the relevant literature to gain a better understanding of the impact of celiac disease on maternal fertility and fetal outcome. Our findings suggest a role for celiac screening in women with unexplained infertility. 

Résumé

La maladie cœliaque est une maladie auto-immune commune qui est souvent sous-estimée chez les femmes enceintes. En raison de la difficulté à mener des études de haute qualité impliquant des patientes enceintes, les preuves soutenant l’association entre la maladie cœliaque et la fertilité maternelle et l’issue de la grossesse, et les avantages du dépistage de la maladie cœliaque dans cette population ne sont pas claires. Par conséquent, nous avons cherché à examiner la littérature pertinente pour mieux comprendre l’impact de la maladie cœliaque sur la fertilité maternelle et l’issue fœtale. Nos résultats suggèrent un rôle pour le dépistage de la maladie cœliaque chez les femmes présentant une infertilité inexpliquée. 

Article Details

Issue
Vol. 7 No. 2 (2017): Women's Health
Section
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